BTRY 717 THEORY OF LINEAR MODELS TIME: MW 8:40-9:55am, B104 Comstock PREREQUISITES: BRTY 409, 421, and 602, or equivalents INSTRUCTOR: Jim Booth, Professor Biological Statistics and Computational Biology 1178 Comstock Hall (Phone: 254-6505) Email: jb383@cornell.edu OFFICE HOURS: TBA COURSE DESCRIPTION: Theory for the analysis of linear models. Properties of the multivariate normal distribution. Distribution theory for quadratic forms. Properties of least squares and maximum likelihood estimates. Methods for fixed effect models of less than full rank. Analysis of balanced and unbalanced mixed effects models. Restricted maximum likelihood estimation. Other potential topics if time permits include: generalized linear models, generalized estimating equations, robust estimation, semi-parametric regression. COURSE TEXT: "Linear Models -- A Mean Model Approach" by Barry Kurt Moser, 1996: Academic Press. ISBN 0-12-508465-X Comment: While I will generally follow the course text, some material may be taken from other sources. GRADING POLICY: Homework will be assigned periodically. Homework assignments may involve data analysis and computation requiring students to use a statistical package. In addition, there will be one in-class exam.